The FK1 domain of FKBP51 in complex with ((1S,5S,6R)-10-((3,5- DICHLOROPHENYL)SULFONYL)-2-oxo-5-vinyl-3,10-DIAZABICYCLO[4.3.1]DECAN- 3-YL)ACETIC acid

Structure

x-ray diffraction · 1 distinct chain · 17% helix, 36% strand (DSSP).

Ligands and binding sites

• RRZ · 2-[(1~{S},5~{S},6~{R})-10-[3,5-bis(chloranyl) phenyl]sulfonyl-5-ethenyl-2-oxidanylidene-3,10-diazabicyclo[4.3.1]decan-3-yl]ethanoic acid · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Compared structures

• 7APT · The Fk1 domain of FKBP51 in complex with ((1S,5S,6R)-10-((3,5-dichlorophenyl)sulfonyl)-2-o… · the same entry in another collection · chain A against A, TM-score 1.00
• Q13451 · AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase FKBP5 (Q13451) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

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• Every structure of UniProt Q13451
• Elsewhere: RCSB PDB 7APT · PDBe 7APT · UniProt Q13451