Research workbench
Native-like genome-containing particle of dwv in acidic pH
Analyse Native-like genome-containing particle of dwv in acidic pH in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7AL3
- Type
- protein
- Length
- 837 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Genome polyprotein
- UniProt
- L0CTV4, E0YTW0, Q7TG18
- Pockets
- 10 · best druggability 0.73
Structure
electron microscopy · 3 distinct chains · 11% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Genome polyprotein | protein | 237 | 11% helix, 24% strand | L0CTV4 |
| B | Genome polyprotein | protein | 229 | 14% helix, 31% strand | E0YTW0 |
| C | Genome polyprotein | protein | 371 | 8% helix, 26% strand | Q7TG18 |
Pockets
10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 91 | 0.73 | 0.95 | 20 | empty |
| 2 | 136 | 0.58 | 0.83 | 28 | empty |
| 3 | 244 | 0.58 | 0.79 | 44 | empty |
| 4 | 62 | 0.53 | 0.87 | 21 | empty |
| 5 | 180 | 0.49 | 0.77 | 30 | empty |
Interfaces
3 interfaces between chains.
- A–C · 4686 Ų buried · 79 hydrogen bonds · protein-protein
- A–B · 1453 Ų buried · 31 hydrogen bonds · protein-protein
- B–C · 1332 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 7AL3 · Native-like genome-containing particle of DWV in acidic pH · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt L0CTV4
- Every structure of UniProt E0YTW0
- Every structure of UniProt Q7TG18
- Elsewhere: RCSB PDB 7AL3 · PDBe 7AL3 · UniProt L0CTV4 · UniProt E0YTW0 · UniProt Q7TG18
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