Research workbench
Opua apo inward-facing
Analyse Opua apo inward-facing in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7AHC
- Type
- protein
- Length
- 1,064 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ABC transporter permease subunit; ABC-type PROLINE/GLYCINE betaine transport system…
- UniProt
- A0A0V8ETW8, A0A0R2NIU5
- Pockets
- 10 · best druggability 0.69
Structure
electron microscopy · 2 distinct chains · 59% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ABC transporter permease subunit | protein | 272 | 77% helix, 0% strand | A0A0V8ETW8 |
| D, C | ABC-type PROLINE/GLYCINE betaine transport system ATPase component | protein | 260 | 41% helix, 14% strand | A0A0R2NIU5 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 136 | 0.69 | 0.89 | 19 | empty |
| 2 | 469 | 0.67 | 0.79 | 41 | empty |
| 3 | 308 | 0.59 | 0.77 | 28 | empty |
| 4 | 271 | 0.58 | 0.77 | 26 | empty |
| 5 | 131 | 0.53 | 0.81 | 23 | empty |
Interfaces
3 interfaces between chains.
- A–B · 2011 Ų buried · 9 hydrogen bonds · protein-protein
- A–D · 920 Ų buried · 12 hydrogen bonds · protein-protein
- B–C · 916 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 7AHC · OpuA apo inward-facing · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0V8ETW8
- Every structure of UniProt A0A0R2NIU5
- Elsewhere: RCSB PDB 7AHC · PDBe 7AHC · UniProt A0A0V8ETW8 · UniProt A0A0R2NIU5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.