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Structure of the N-domain of the K+/H+ antiporter subunit khtt at pH 6.5

Analyse Structure of the N-domain of the K+/H+ antiporter subunit khtt at pH 6.5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7AGW
Type: protein
Length: 140 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: K(+)/H(+) antiporter subunit khtt
UniProt: O07535
Pockets: 1 · best druggability 0.80

Structure

x-ray diffraction · 2 distinct chains · 16% helix, 52% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	K(+)/H(+) antiporter subunit khtt	protein	69	16% helix, 49% strand	O07535
B	K(+)/H(+) antiporter subunit khtt	protein	71	17% helix, 55% strand	O07535

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	111	0.80	0.98	21	empty

Interfaces

1 interface between chains.

A–B · 1420 Å² buried · 18 hydrogen bonds · protein-protein

Compared structures

7AGW · Structure of the N-domain of the K+/H+ antiporter subunit KhtT at pH 6.5 · the same entry in another collection · chain A against A, TM-score 1.00
O07535 · AlphaFold monomer V2.0 prediction for K(+)/H(+) antiporter subunit khtt (O07535) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O07535
Elsewhere: RCSB PDB 7AGW · PDBe 7AGW · UniProt O07535

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