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Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2

Analyse Structural evolution of the tissue-specific U2AF2 paralog and alternative… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7AAO
Type: protein
Length: 122 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: U2 snrnp auxiliary factor large subunit
UniProt: Q8T8Y4
Pockets: 1 · best druggability 0.57

Structure

solution nmr · 1 distinct chain · 15% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	U2 snrnp auxiliary factor large subunit	protein	122	15% helix, 23% strand	Q8T8Y4

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	228	0.57	0.79	34	empty

Compared structures

7AAO · Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8T8Y4
Elsewhere: RCSB PDB 7AAO · PDBe 7AAO · UniProt Q8T8Y4

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