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Structure of apo telomerase from candida tropicalis truncated from C- terminal domain

Analyse Structure of apo telomerase from candida tropicalis truncated from C- terminal… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6ZD2
Type: protein
Length: 526 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Telomerase reverse transcriptase
EC: 2.7.7.49
UniProt: C5MCQ7
Ligands: NA
Pockets: 6 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Telomerase reverse transcriptase (EC 2.7.7.49)	protein	526	50% helix, 17% strand	C5MCQ7

Ligands and binding sites

NA · Sodium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	249	0.63	0.81	33	empty
2	179	0.48	0.76	28	empty
3	176	0.44	0.75	24	empty
4	59	0.42	0.81	16	empty
5	77	0.35	0.76	19	empty

Compared structures

6ZD2 · Structure of apo telomerase from Candida Tropicalis truncated from C-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C5MCQ7
Elsewhere: RCSB PDB 6ZD2 · PDBe 6ZD2 · UniProt C5MCQ7

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