Research workbench
Structure of apo telomerase from candida tropicalis
Analyse Structure of apo telomerase from candida tropicalis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6ZD1
- Type
- protein
- Length
- 645 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Telomerase reverse transcriptase
- EC
- 2.7.7.49
- UniProt
- C5MCQ7
- Pockets
- 7 · best druggability 0.82
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomerase reverse transcriptase (EC 2.7.7.49) | protein | 645 | 51% helix, 14% strand | C5MCQ7 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1109 | 0.82 | 0.84 | 124 | empty |
| 2 | 705 | 0.73 | 0.79 | 84 | empty |
| 3 | 83 | 0.66 | 0.91 | 26 | empty |
| 4 | 154 | 0.50 | 0.78 | 16 | empty |
| 5 | 66 | 0.40 | 0.80 | 17 | empty |
Modifications
Observed in the structure: 11 modified (engineered).
Compared structures
- 6ZD1 · Structure of apo telomerase from Candida Tropicalis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C5MCQ7
- Elsewhere: RCSB PDB 6ZD1 · PDBe 6ZD1 · UniProt C5MCQ7
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