Research workbench
Crystal structure of an archaeal fructose 1,6-bisphosphate aldolase
Analyse Crystal structure of an archaeal fructose 1,6-bisphosphate aldolase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1OJX
- Type
- protein
- Length
- 2,502 residues
- Chains
- 10
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fructose-bisphosphate aldolase class I
- EC
- 4.1.2.13
- UniProt
- P58315
- Pockets
- 20 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, F, G, H, I, J | Fructose-bisphosphate aldolase class I (EC 4.1.2.13) | protein | 250 | 47% helix, 16% strand | P58315 |
| E | Fructose-bisphosphate aldolase class I (EC 4.1.2.13) | protein | 252 | 47% helix, 16% strand | P58315 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1021 | 0.73 | 0.76 | 75 | empty |
| 2 | 172 | 0.66 | 0.86 | 31 | empty |
| 3 | 628 | 0.66 | 0.75 | 65 | empty |
| 4 | 475 | 0.65 | 0.78 | 40 | empty |
| 5 | 463 | 0.65 | 0.78 | 37 | empty |
Interfaces
15 interfaces between chains.
- F–J · 1566 Ų buried · 20 hydrogen bonds · protein-protein
- I–J · 1563 Ų buried · 21 hydrogen bonds · protein-protein
- D–E · 1560 Ų buried · 20 hydrogen bonds · protein-protein
- B–C · 1559 Ų buried · 19 hydrogen bonds · protein-protein
- G–H · 1557 Ų buried · 20 hydrogen bonds · protein-protein
Compared structures
- 1OJX · Crystal structure of an Archaeal fructose 1,6-bisphosphate aldolase · the same entry in another collection · chain J against J, TM-score 1.00
- P58315 · AlphaFold monomer V2.0 prediction for fructose-bisphosphate aldolase class 1 (P58315) · a predicted model of the same protein · chain I against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P58315
- Elsewhere: RCSB PDB 1OJX · PDBe 1OJX · UniProt P58315
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.