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Allostery through DNA drives phenotype switching

Analyse Allostery through DNA drives phenotype switching in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6Z0S
Type
DNA
Length
168 nucleotides
Chains
2
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Comg promoter DNA - strand a; Comg promoter DNA - strand B
Pockets
1 · best druggability 0.25

Structure

electron microscopy · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
AComg promoter DNA - strand adna84——
BComg promoter DNA - strand Bdna84——

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1620.250.7212empty

Interfaces

1 interface between chains.

  • A–B · 3764 Ų buried · 290 hydrogen bonds · nucleic-nucleic

Compared structures

  • 6Z0S · Allostery through DNA drives phenotype switching · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

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