Research workbench
Structure of chloroflexus aggregans flavin based fluorescent protein (cagfbfp) Q148K variant (space group P21)
Analyse Structure of chloroflexus aggregans flavin based fluorescent protein (cagfbfp)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6YXB
- Type
- protein
- Length
- 416 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Multi-sensor hybrid histidine kinase
- UniProt
- B8GAY9
- Ligands
- FMN, SO4
- Pockets
- 6 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Multi-sensor hybrid histidine kinase | protein | 104 | 27% helix, 37% strand | B8GAY9 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 4 copies · chains A, B, C, D
- SO4 · Sulfate ion · ion · 5 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 193 | 0.76 | 0.91 | 31 | FMN |
| 2 | 1045 | 0.73 | 0.76 | 60 | empty |
| 3 | 170 | 0.72 | 0.90 | 22 | FMN |
| 4 | 166 | 0.72 | 0.90 | 22 | FMN |
| 5 | 182 | 0.71 | 0.89 | 24 | FMN |
Interfaces
3 interfaces between chains.
- C–D · 774 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 773 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 269 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6YXB · Structure of Chloroflexus aggregans flavin based fluorescent protein (CagFbFP) Q148K… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B8GAY9
- Elsewhere: RCSB PDB 6YXB · PDBe 6YXB · UniProt B8GAY9
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