Crystal structure of native phycocyanin from T. elongatus in spacegroup P63 at 1.8 ångströms

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Ligands and binding sites

• CYC · Phycocyanobilin · ligand · 3 copies · chains A, B
• EDO · 1,2-ethanediol · additive · 7 copies · chains A, B
• PGE · Triethylene glycol · additive · 4 copies · chains A, B
• GOL · Glycerol · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Interfaces

1 interface between chains.

• A–B · 1616 Ų buried · 14 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 cofactor, 1 modified (phycocyanobilin attachment, nonstandard).

Compared structures

• 6YQ8 · Crystal structure of native Phycocyanin from T. elongatus in spacegroup P63 at 1.8… · the same entry in another collection · chain A against A, TM-score 1.00
• P50033 · AlphaFold monomer V2.0 prediction for C-phycocyanin beta subunit (P50033) · a predicted model of the same protein · chain B against A, TM-score 1.00
• P50032 · AlphaFold monomer V2.0 prediction for C-phycocyanin alpha subunit (P50032) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P50032
• Every structure of UniProt P50033
• Elsewhere: RCSB PDB 6YQ8 · PDBe 6YQ8 · UniProt P50032 · UniProt P50033