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Structure of CDC14 in complex with tungstate

Analyse Structure of CDC14 in complex with tungstate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1OHD
Type: protein
Length: 338 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CDC14B2 phosphatase
UniProt: O60729
Ligands: WO4
Pockets: 3 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CDC14B2 phosphatase	protein	338	41% helix, 14% strand	O60729

Ligands and binding sites

WO4 · Tungstate(vi)ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	163	0.62	0.84	23	empty
2	157	0.46	0.76	33	empty
3	71	0.31	0.74	16	WO4

Compared structures

1OHD · structure of cdc14 in complex with tungstate · the same entry in another collection · chain A against A, TM-score 1.00
O60729 · AlphaFold monomer V2.0 prediction for dual specificity protein phosphatase CDC14B (O60729) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60729
Elsewhere: RCSB PDB 1OHD · PDBe 1OHD · UniProt O60729

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