Crystal structure of a parallel hexameric coiled coil cc-TYPE2-(TAID)2

Structure

x-ray diffraction · 1 distinct chain · 93% helix, 0% strand (DSSP).

Ligands and binding sites

• ACE · Acetyl group · ligand · 6 copies · chains A, F, B, C, D, E
• NH2 · Amino group · ion · 6 copies · chains A, B, C, D, E, F
• GOL · Glycerol · additive · 2 copies · chains A, B, C, D, E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Interfaces

6 interfaces between chains.

• B–C · 754 Ų buried · 5 hydrogen bonds · protein-protein
• A–B · 735 Ų buried · 2 hydrogen bonds · protein-protein
• A–F · 727 Ų buried · 2 hydrogen bonds · protein-protein
• E–F · 714 Ų buried · 2 hydrogen bonds · protein-protein
• D–E · 702 Ų buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 covalent (covalent ligand).

Compared structures

• 6YB2 · Crystal structure of a parallel hexameric coiled coil CC-Type2-(TaId)2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Elsewhere: RCSB PDB 6YB2 · PDBe 6YB2