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Crystal structure of a parallel hexameric coiled coil cc-TYPE2-(TASD)2

Analyse Crystal structure of a parallel hexameric coiled coil cc-TYPE2-(TASD)2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6YB0
Type: protein
Length: 442 residues
Chains: 12
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cc-TYPE2-(TASD)2
Pockets: 4 · best druggability 0.88

Structure

x-ray diffraction · 2 distinct chains · 95% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C, D, E, G, H, I, J, K, L	Cc-TYPE2-(TASD)2	protein	37	95% helix, 0% strand	—
B, F	Cc-TYPE2-(TASD)2	protein	36	94% helix, 0% strand	—

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	847	0.88	0.90	83	empty
2	827	0.88	0.90	80	empty
3	384	0.67	0.80	50	empty
4	74	0.43	0.80	14	empty

Interfaces

16 interfaces between chains.

A–F · 898 Å² buried · 6 hydrogen bonds · protein-protein
B–C · 893 Å² buried · 4 hydrogen bonds · protein-protein
I–J · 888 Å² buried · 3 hydrogen bonds · protein-protein
G–L · 887 Å² buried · 6 hydrogen bonds · protein-protein
D–E · 885 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

6YB0 · Crystal structure of a parallel hexameric coiled coil CC-Type2-(TaSd)2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6YB0 · PDBe 6YB0

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