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Structure of glutamate transporter homologue glttk in sodium only condition

Analyse Structure of glutamate transporter homologue glttk in sodium only condition in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6XWR
Type: protein
Length: 1,278 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: PROTON/GLUTAMATE symporter, sdf family
UniProt: Q5JID0
Pockets: 16 · best druggability 0.88

Structure

electron microscopy · 1 distinct chain · 76% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	PROTON/GLUTAMATE symporter, sdf family	protein	426	76% helix, 0% strand	Q5JID0

Pockets

16 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	526	0.88	0.93	40	empty
2	339	0.62	0.78	55	empty
3	361	0.59	0.75	39	empty
4	270	0.57	0.77	34	empty
5	285	0.55	0.76	36	empty

Interfaces

3 interfaces between chains.

A–B · 1204 Å² buried · 10 hydrogen bonds · protein-protein
A–C · 1183 Å² buried · 11 hydrogen bonds · protein-protein
B–C · 1145 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

6XWR · Structure of glutamate transporter homologue GltTk in sodium only condition · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5JID0
Elsewhere: RCSB PDB 6XWR · PDBe 6XWR · UniProt Q5JID0

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