Research workbench
Computationally designed right-handed ALPHA/ALPHA homotrimeric toroid with 3 repeats per subunit
Analyse Computationally designed right-handed ALPHA/ALPHA homotrimeric toroid with 3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6XR2
- Type
- protein
- Length
- 1,009 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- DTOR_3X57R
- Pockets
- 10 · best druggability 0.72
Structure
x-ray diffraction · 6 distinct chains · 88% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DTOR_3X57R | protein | 169 | 88% helix, 0% strand | — |
| B | DTOR_3X57R | protein | 167 | 92% helix, 0% strand | — |
| C | DTOR_3X57R | protein | 170 | 88% helix, 0% strand | — |
| D | DTOR_3X57R | protein | 167 | 87% helix, 0% strand | — |
| E | DTOR_3X57R | protein | 171 | 83% helix, 0% strand | — |
| F | DTOR_3X57R | protein | 165 | 87% helix, 0% strand | — |
Pockets
10 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 894 | 0.72 | 0.77 | 83 | empty |
| 2 | 237 | 0.48 | 0.74 | 42 | empty |
| 3 | 59 | 0.40 | 0.81 | 19 | empty |
| 4 | 65 | 0.35 | 0.77 | 12 | empty |
| 5 | 89 | 0.35 | 0.74 | 22 | empty |
Interfaces
8 interfaces between chains.
- D–E · 1112 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 1085 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 957 Ų buried · 3 hydrogen bonds · protein-protein
- A–C · 925 Ų buried · 4 hydrogen bonds · protein-protein
- E–F · 924 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6XR2 · Computationally designed right-handed alpha/alpha homotrimeric toroid with 3 repeats per… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6XR2 · PDBe 6XR2
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