Research workbench
Crystal structure of the PEX4-PEX22 protein complex from arabidopsis thaliana
Analyse Crystal structure of the PEX4-PEX22 protein complex from arabidopsis thaliana in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6XOD
- Type
- protein
- Length
- 320 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein peroxin-4; Peroxisome biogenesis protein 22
- EC
- 2.3.2.23
- UniProt
- Q8LGF7, Q9LSX7
- Pockets
- 1 · best druggability 0.36
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein peroxin-4 (EC 2.3.2.23) | protein | 154 | 35% helix, 17% strand | Q8LGF7 |
| B | Peroxisome biogenesis protein 22 | protein | 166 | 39% helix, 20% strand | Q9LSX7 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 61 | 0.36 | 0.78 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 829 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 6XOD · Crystal structure of the PEX4-PEX22 protein complex from Arabidopsis thaliana · the same entry in another collection · chain A against A, TM-score 1.00
- Q8LGF7 · AlphaFold monomer V2.0 prediction for protein peroxin-4 (Q8LGF7) · a predicted model of the same protein · chain A against A, TM-score 0.97
- Q9LSX7 · AlphaFold monomer V2.0 prediction for peroxisome biogenesis protein 22 (Q9LSX7) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8LGF7
- Every structure of UniProt Q9LSX7
- Elsewhere: RCSB PDB 6XOD · PDBe 6XOD · UniProt Q8LGF7 · UniProt Q9LSX7
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