Research workbench
7,8-dihydroneopterin triphosphate epimerase
Analyse 7,8-dihydroneopterin triphosphate epimerase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1B9L
- Type
- protein
- Length
- 952 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein (epimerase)
- UniProt
- P0AC19
- Pockets
- 12 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H | Protein (epimerase) | protein | 119 | 32% helix, 39% strand | P0AC19 |
Pockets
12 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 748 | 0.78 | 0.83 | 94 | empty |
| 2 | 405 | 0.72 | 0.84 | 57 | empty |
| 3 | 257 | 0.66 | 0.83 | 30 | empty |
| 4 | 90 | 0.51 | 0.84 | 18 | empty |
| 5 | 101 | 0.51 | 0.82 | 18 | empty |
Interfaces
16 interfaces between chains.
- C–D · 1116 Ų buried · 25 hydrogen bonds · protein-protein
- E–F · 1111 Ų buried · 24 hydrogen bonds · protein-protein
- A–C · 1105 Ų buried · 24 hydrogen bonds · protein-protein
- A–B · 1103 Ų buried · 22 hydrogen bonds · protein-protein
- F–H · 1096 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0AC19
- Elsewhere: RCSB PDB 1B9L · PDBe 1B9L · UniProt P0AC19
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