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Structure of a anophensin from anopheles stephensi

Analyse Structure of a anophensin from anopheles stephensi in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6XMB
Type: protein
Length: 349 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Anophensin
UniProt: A5HUP6
Pockets: 2 · best druggability 0.52

Structure

x-ray diffraction · 3 distinct chains · 78% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Anophensin	protein	118	77% helix, 2% strand	A5HUP6
B	Anophensin	protein	118	79% helix, 2% strand	A5HUP6
C	Anophensin	protein	113	77% helix, 0% strand	A5HUP6

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	279	0.52	0.74	34	empty
2	83	0.40	0.78	17	empty

Interfaces

2 interfaces between chains.

A–B · 1956 Å² buried · 7 hydrogen bonds · protein-protein
B–C · 117 Å² buried · 1 hydrogen bond · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

6XMB · Structure of an anophensin from Anopheles stephensi · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A5HUP6
Elsewhere: RCSB PDB 6XMB · PDBe 6XMB · UniProt A5HUP6

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