Research workbench

Free conformation AB2 of the IgE spe-7

Analyse Free conformation AB2 of the IgE spe-7 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1OCW
Type: protein
Length: 230 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Immunoglobulin E
Pockets: 1 · best druggability 0.53

Structure

x-ray diffraction · 2 distinct chains · 1% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
H	Immunoglobulin E	protein	120	0% helix, 36% strand	—
L	Immunoglobulin E	protein	110	3% helix, 52% strand	—

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.53	0.88	12	empty

Interfaces

1 interface between chains.

H–L · 997 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1OCW · Free conformation Ab2 of the IgE SPE-7 · the same entry in another collection · chain H against H, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1OCW · PDBe 1OCW

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.