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Crystal structure of a fluorescent single chain fv chimera

Analyse Crystal structure of a fluorescent single chain fv chimera in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6WZN
Type: protein
Length: 459 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Fluorescent single chain fv chimera
Ligands: CRQ
Pockets: 6 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 5% helix, 52% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Fluorescent single chain fv chimera	protein	459	5% helix, 52% strand	—

Ligands and binding sites

CRQ · [2-(3-carbamoyl-1-imino-propyl)-4-(4-hydroxy-benzylidene)-5-oxo-4,5-dihydro-imidazol-1-yl]-acetic acid · ligand · chains A
GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	97	0.77	0.97	27	CRQ
2	277	0.58	0.78	26	empty
3	178	0.46	0.75	27	GOL
4	108	0.35	0.73	20	empty
5	88	0.34	0.74	20	GOL

Modifications

Observed in the structure: 2 cofactor (chromophore).

Compared structures

6WZN · Crystal Structure of a Fluorescent Single Chain Fv Chimera · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6WZN · PDBe 6WZN

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