Human calcium and integrin binding protein 3 bound to TMC1 residues 303-347

Structure

x-ray diffraction · 2 distinct chains · 59% helix, 2% strand (DSSP).

Ligands and binding sites

• MG · Magnesium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1666 Ų buried · 18 hydrogen bonds · protein-protein

Compared structures

• 6WUD · Human Calcium and Integrin Binding Protein 3 Bound to TMC1 Residues 303-347 · the same entry in another collection · chain A against A, TM-score 1.00
• Q96Q77 · AlphaFold monomer V2.0 prediction for calcium and integrin-binding family member 3… · a predicted model of the same protein · chain A against A, TM-score 0.96
• Q8R4P5 · AlphaFold monomer V2.0 prediction for transmembrane channel-like protein 1 (Q8R4P5) · a predicted model of the same protein · chain B against A, TM-score 0.93

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q96Q77
• Every structure of UniProt Q8R4P5
• Elsewhere: RCSB PDB 6WUD · PDBe 6WUD · UniProt Q96Q77 · UniProt Q8R4P5