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Structure of apo laindy

Analyse Structure of apo laindy in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6WU1
Type: protein
Length: 978 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dass family sodium-coupled anion symporter
UniProt: A0A3A9Y7Q2
Ligands: D10
Pockets: 10 · best druggability 0.77

Structure

electron microscopy · 1 distinct chain · 71% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Dass family sodium-coupled anion symporter	protein	489	71% helix, 1% strand	A0A3A9Y7Q2

Ligands and binding sites

D10 · Decane · ligand · 8 copies · chains A, B
HEX · Hexane · additive · 10 copies · chains A, B
OCT · N-octane · additive · 6 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	949	0.77	0.79	134	empty
2	351	0.59	0.76	33	empty
3	308	0.58	0.77	35	empty
4	186	0.56	0.79	25	D10
5	148	0.55	0.81	19	D10, OCT

Interfaces

1 interface between chains.

A–B · 2682 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

6WU1 · Structure of apo LaINDY · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A3A9Y7Q2
Elsewhere: RCSB PDB 6WU1 · PDBe 6WU1 · UniProt A0A3A9Y7Q2

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