Research workbench
Crystal structure of a cysteine desulfurase sufs from stenotrophomonas maltophilia K279A
Analyse Crystal structure of a cysteine desulfurase sufs from stenotrophomonas… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6WCI
- Type
- protein
- Length
- 805 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cysteine desulfurase
- EC
- 2.8.1.7
- UniProt
- B2FS04
- Ligands
- SO4
- Pockets
- 4 · best druggability 0.81
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cysteine desulfurase (EC 2.8.1.7) | protein | 402 | 44% helix, 19% strand | B2FS04 |
| B | Cysteine desulfurase (EC 2.8.1.7) | protein | 403 | 43% helix, 19% strand | B2FS04 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 206 | 0.81 | 0.95 | 38 | EDO |
| 2 | 131 | 0.64 | 0.88 | 23 | empty |
| 3 | 219 | 0.62 | 0.82 | 33 | empty |
| 4 | 93 | 0.39 | 0.76 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 3519 Ų buried · 50 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (cofactor, oxidation).
Compared structures
- 6WCI · Crystal structure of a cysteine desulfurase SufS from Stenotrophomonas maltophilia K279a · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2FS04
- Elsewhere: RCSB PDB 6WCI · PDBe 6WCI · UniProt B2FS04
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