Research workbench
Crystal structure of MRECK(CC4) in fusion with engineered mbp at medium resolution
Analyse Crystal structure of MRECK(CC4) in fusion with engineered mbp at medium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6WBH
- Type
- protein
- Length
- 431 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Maltodextrin-binding PROTEIN,REVERSION-inducing cysteine- rich protein with kazal motifs…
- UniProt
- A0A376KDN7, Q9Z0J1
- Ligands
- GLC, ZN, CL
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · 1 distinct chain · 49% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Maltodextrin-binding PROTEIN,REVERSION-inducing cysteine- rich protein with kazal motifs fusion | protein | 431 | 49% helix, 18% strand | A0A376KDN7, Q9Z0J1 |
Ligands and binding sites
- GLC · alpha-D-glucopyranose · sugar · 2 copies · chains A
- ZN · Zinc ion · metal · 2 copies · chains A
- CL · Chloride ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 338 | 0.71 | 0.84 | 35 | GLC |
| 2 | 623 | 0.66 | 0.76 | 67 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Compared structures
- 6WBH · Crystal structure of mRECK(CC4) in fusion with engineered MBP at medium resolution · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Z0J1 · AlphaFold monomer V2.0 prediction for reversion-inducing cysteine- rich protein with… · a predicted model of the same protein · chain A against A, TM-score 0.30
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A376KDN7
- Every structure of UniProt Q9Z0J1
- Elsewhere: RCSB PDB 6WBH · PDBe 6WBH · UniProt A0A376KDN7 · UniProt Q9Z0J1
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