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Crystal structure of uroporphyrinogen III decarboxylate (heme) from stenotrophomonas maltophilia

Analyse Crystal structure of uroporphyrinogen III decarboxylate (heme) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6W2O
Type: protein
Length: 355 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uroporphyrinogen decarboxylase
EC: 4.1.1.37
UniProt: B2FQJ0
Ligands: SO4, CL
Pockets: 1 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 52% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uroporphyrinogen decarboxylase (EC 4.1.1.37)	protein	355	52% helix, 10% strand	B2FQJ0

Ligands and binding sites

SO4 · Sulfate ion · ion · 4 copies · chains A
CL · Chloride ion · ion · 2 copies · chains A
EDO · 1,2-ethanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	533	0.72	0.80	37	EDO, SO4, CL

Compared structures

6W2O · Crystal structure of uroporphyrinogen III decarboxylate (hemE) from Stenotrophomonas… · the same entry in another collection · chain A against A, TM-score 1.00

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Every structure of UniProt B2FQJ0
Elsewhere: RCSB PDB 6W2O · PDBe 6W2O · UniProt B2FQJ0

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