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Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81

Analyse Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6VWB
Type: protein
Length: 90 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Crossover junction endonuclease MUS81
EC: 3.1.22.-
UniProt: Q96NY9
Pockets: 1 · best druggability 0.34

Structure

solution nmr · 1 distinct chain · 58% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Crossover junction endonuclease MUS81 (EC 3.1.22.-)	protein	90	58% helix, 0% strand	Q96NY9

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.34	0.77	10	empty

Compared structures

6VWB · Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81 · the same entry in another collection · chain A against A, TM-score 1.00
Q96NY9 · AlphaFold monomer V2.0 prediction for crossover junction endonuclease MUS81 (Q96NY9) · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96NY9
Elsewhere: RCSB PDB 6VWB · PDBe 6VWB · UniProt Q96NY9

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