Research workbench
Contact-dependent growth inhibition toxin-immunity protein complex from from E. COLI 3006, full-length
Analyse Contact-dependent growth inhibition toxin-immunity protein complex from from E.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6VEK
- Type
- protein
- Length
- 474 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Contact-dependent toxin cdia; Contact-dependent immunity protein cdii
- UniProt
- A0A4T7DH52, A0A2A2C800
- Pockets
- 4 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 63% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Contact-dependent toxin cdia | protein | 321 | 60% helix, 14% strand | A0A4T7DH52 |
| I | Contact-dependent immunity protein cdii | protein | 153 | 69% helix, 0% strand | A0A2A2C800 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 324 | 0.59 | 0.77 | 34 | empty |
| 2 | 243 | 0.56 | 0.78 | 34 | empty |
| 3 | 75 | 0.54 | 0.86 | 22 | empty |
| 4 | 66 | 0.39 | 0.79 | 20 | empty |
Interfaces
1 interface between chains.
- A–I · 1890 Ų buried · 29 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6VEK · Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A4T7DH52
- Every structure of UniProt A0A2A2C800
- Elsewhere: RCSB PDB 6VEK · PDBe 6VEK · UniProt A0A4T7DH52 · UniProt A0A2A2C800
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