Research workbench
Crystal structure of the class a beta-lactamse L2 from stenotrophomonas maltophilia at 1.51 ångström
Analyse Crystal structure of the class a beta-lactamse L2 from stenotrophomonas… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1O7E
- Type
- protein
- Length
- 539 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L2 beta lactamase
- EC
- 3.5.2.6
- UniProt
- Q9RBQ1
- Ligands
- SO4
- Pockets
- 8 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L2 beta lactamase (EC 3.5.2.6) | protein | 267 | 45% helix, 20% strand | Q9RBQ1 |
| B | L2 beta lactamase (EC 3.5.2.6) | protein | 272 | 46% helix, 19% strand | Q9RBQ1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 210 | 0.56 | 0.79 | 32 | empty |
| 2 | 83 | 0.52 | 0.84 | 21 | empty |
| 3 | 117 | 0.39 | 0.75 | 17 | empty |
| 4 | 77 | 0.33 | 0.75 | 19 | SO4 |
| 5 | 64 | 0.33 | 0.77 | 19 | SO4 |
Interfaces
1 interface between chains.
- A–B · 1015 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 1O7E · Crystal structure of the class A beta-lactamse L2 from Stenotrophomonas maltophilia at… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9RBQ1
- Elsewhere: RCSB PDB 1O7E · PDBe 1O7E · UniProt Q9RBQ1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.