Research workbench
Lipophilic envelope-spanning tunnel protein (letb), domains MCE2-MCE3
Analyse Lipophilic envelope-spanning tunnel protein (letb), domains MCE2-MCE3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6VCI
- Type
- protein
- Length
- 429 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lipophilic envelope-spanning tunnel protein letb
- UniProt
- P76272
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | Lipophilic envelope-spanning tunnel protein letb | protein | 214 | 9% helix, 45% strand | P76272 |
| A | Lipophilic envelope-spanning tunnel protein letb | protein | 215 | 12% helix, 46% strand | P76272 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 606 | 0.67 | 0.77 | 56 | empty |
| 2 | 95 | 0.36 | 0.75 | 24 | empty |
| 3 | 78 | 0.31 | 0.74 | 19 | empty |
Interfaces
1 interface between chains.
- C–A · 267 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6VCI · Lipophilic envelope-spanning tunnel protein (LetB), domains MCE2-MCE3 · the same entry in another collection · chain C against C, TM-score 1.00
- P76272 · AlphaFold monomer V2.0 prediction for intermembrane transport protein yebt (P76272) · a predicted model of the same protein · chain C against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P76272
- Elsewhere: RCSB PDB 6VCI · PDBe 6VCI · UniProt P76272
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