Research workbench
Solution structure of the tau pre-mRNA exon 10 splicing regulatory element bound to MH5
Analyse Solution structure of the tau pre-mRNA exon 10 splicing regulatory element… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6VA2
- Type
- RNA
- Length
- 21 nucleotides
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3'); RNA…
- Ligands
- QSV
Structure
solution nmr · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA (5'-R(*CP*CP*GP*GP*CP*AP*GP*UP*GP*UP*G)-3') | rna | 11 | — | — |
| B | RNA (5'-R(*CP*AP*CP*AP*CP*GP*UP*CP*GP*G)-3') | rna | 10 | — | — |
Ligands and binding sites
- QSV · (2E,2'E)-2,2'-{dibenzo[b,d]thiene-2,8-diyldi[(1E)eth-1-yl-1-ylidene]}bis(N-methylhydrazine-1-carboximidamide) · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 517 Ų buried · 45 hydrogen bonds · nucleic-nucleic
Compared structures
- 6VA2 · Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MH5 · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6VA2 · PDBe 6VA2
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