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Structure of a sodium potassium ion channel

Analyse Structure of a sodium potassium ion channel in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6V8Y
Type: protein
Length: 184 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Potassium channel protein
UniProt: A0A164U772
Ligands: K, NA
Pockets: 2 · best druggability 0.33

Structure

x-ray diffraction · 2 distinct chains · 79% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Potassium channel protein	protein	90	80% helix, 0% strand	A0A164U772
B	Potassium channel protein	protein	94	78% helix, 0% strand	A0A164U772

Ligands and binding sites

K · Potassium ion · metal · 3 copies · chains A, B
NA · Sodium ion · metal · 2 copies · chains A, B
MPD · (4S)-2-methyl-2,4-pentanediol · additive · 8 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.33	0.78	11	MPD
2	62	0.28	0.73	16	empty

Interfaces

1 interface between chains.

A–B · 1060 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

6V8Y · Structure of a Sodium Potassium ion Channel · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A164U772
Elsewhere: RCSB PDB 6V8Y · PDBe 6V8Y · UniProt A0A164U772

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