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Solution NMR structure of dictyostelium discoideum SKP1A (truncated) dimer

Analyse Solution NMR structure of dictyostelium discoideum SKP1A (truncated) dimer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6V88
Type: protein
Length: 232 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Scf ubiquitin ligase complex protein SKP1A
UniProt: P52285
Pockets: 2 · best druggability 0.42

Structure

solution nmr · 1 distinct chain · 57% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Scf ubiquitin ligase complex protein SKP1A	protein	116	57% helix, 9% strand	P52285

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	122	0.42	0.76	16	empty
2	125	0.41	0.75	17	empty

Interfaces

1 interface between chains.

A–B · 790 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

6V88 · Solution NMR structure of Dictyostelium discoideum Skp1A (truncated) dimer · the same entry in another collection · chain A against A, TM-score 1.00
P52285 · AlphaFold monomer V2.0 prediction for scf ubiquitin ligase complex protein SKP1A (P52285) · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52285
Elsewhere: RCSB PDB 6V88 · PDBe 6V88 · UniProt P52285

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