Research workbench
Crystal structure of a nudix hydrolase from M. smegmatis, renu
Analyse Crystal structure of a nudix hydrolase from M. smegmatis, renu in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6UUF
- Type
- protein
- Length
- 316 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nudix hydrolase, renu
- UniProt
- I7FED3
- Pockets
- 2 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 25% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nudix hydrolase, renu | protein | 161 | 23% helix, 39% strand | I7FED3 |
| B | Nudix hydrolase, renu | protein | 155 | 26% helix, 37% strand | I7FED3 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 470 | 0.72 | 0.82 | 53 | empty |
| 2 | 226 | 0.53 | 0.77 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 614 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 6UUF · Crystal structure of a Nudix Hydrolase from M. Smegmatis, RenU · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I7FED3
- Elsewhere: RCSB PDB 6UUF · PDBe 6UUF · UniProt I7FED3
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