Research workbench
Structure of vx-phosphonylated hache in complex with oxime reactivator RS194B
Analyse Structure of vx-phosphonylated hache in complex with oxime reactivator RS194B in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6U37
- Type
- protein
- Length
- 1,080 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P22303
- Ligands
- VX, PQV, NO3
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 540 | — | P22303 |
Ligands and binding sites
- VX · O-ethylmethylphosphonic acid ester group · ligand · 2 copies · chains A, B
- PQV · (2E)-N-[2-(azepan-1-yl)ethyl]-2-(hydroxyimino)acetamide · ligand · 2 copies · chains A, B
- NO3 · Nitrate ion · ion · 3 copies · chains A
- GOL · Glycerol · additive · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6U37 · Structure of VX-phosphonylated hAChE in complex with oxime reactivator RS194B · the same entry in another collection · chain A against A, TM-score 1.00
- P22303 · AlphaFold monomer V2.0 prediction for acetylcholinesterase (P22303) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22303
- Elsewhere: RCSB PDB 6U37 · PDBe 6U37 · UniProt P22303
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