Research workbench
Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia COLI NMR, restrained regularized mean structure
Analyse Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1O2F
- Type
- protein
- Length
- 227 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Pts system, glucose-specific iia component; Pts system, glucose-specific iibc component
- EC
- 2.7.1.69
- UniProt
- P69783, P69786
- Ligands
- PO3
- Pockets
- 1 · best druggability 0.36
Structure
solution nmr · 2 distinct chains · 24% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pts system, glucose-specific iia component (EC 2.7.1.69) | protein | 150 | 14% helix, 41% strand | P69783 |
| B | Pts system, glucose-specific iibc component (EC 2.7.1.69) | protein | 77 | 44% helix, 27% strand | P69786 |
Ligands and binding sites
- PO3 · Phosphite ion · ion · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 66 | 0.36 | 0.78 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 608 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 1O2F · Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia COLI NMR… · the same entry in another collection · chain B against B, TM-score 1.00
- P69783 · AlphaFold monomer V2.0 prediction for pts system glucose-specific eiia component (P69783) · a predicted model of the same protein · chain A against A, TM-score 0.99
- P69786 · AlphaFold monomer V2.0 prediction for pts system glucose-specific eiicb component (P69786) · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P69783
- Every structure of UniProt P69786
- Elsewhere: RCSB PDB 1O2F · PDBe 1O2F · UniProt P69783 · UniProt P69786
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