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Chaetomium thermophilum udp-glucose glucosyl transferase (uggt) double cysteine mutant G177C/A786C.

Analyse Chaetomium thermophilum udp-glucose glucosyl transferase (uggt) double cysteine… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6TS8
Type: protein
Length: 2,508 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Udp-glucose-glycoprotein glucosyltransferase-like protein
UniProt: G0SB58
Pockets: 20 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 29% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Udp-glucose-glycoprotein glucosyltransferase-like protein	protein	1254	29% helix, 13% strand	G0SB58

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1052	0.84	0.85	126	empty
2	763	0.82	0.85	85	empty
3	396	0.75	0.85	56	empty
4	84	0.74	0.96	28	empty
5	76	0.74	0.97	28	empty

Interfaces

1 interface between chains.

A–B · 808 Å² buried · 6 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

6TS8 · Chaetomium thermophilum UDP-Glucose Glucosyl Transferase (UGGT) double cysteine mutant… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G0SB58
Elsewhere: RCSB PDB 6TS8 · PDBe 6TS8 · UniProt G0SB58

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