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Structure of E70A mutant of REX8A from paenibacillus barcinonensis.

Analyse Structure of E70A mutant of REX8A from paenibacillus barcinonensis. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6TPP
Type: protein
Length: 754 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Reducing-end xylose-releasing exo-oligoxylanase REX8A
EC: 3.2.1.156
UniProt: A0A0S2UQQ5
Pockets: 4 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 51% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Reducing-end xylose-releasing exo-oligoxylanase REX8A (EC 3.2.1.156)	protein	377	51% helix, 10% strand	A0A0S2UQQ5

Ligands and binding sites

EDO · 1,2-ethanediol · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1154	0.83	0.84	111	EDO
2	67	0.76	0.99	20	empty
3	60	0.75	1.00	19	empty
4	205	0.46	0.74	26	empty

Interfaces

1 interface between chains.

A–B · 566 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

6TPP · Structure of E70A mutant of Rex8A from Paenibacillus barci nsis. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0S2UQQ5
Elsewhere: RCSB PDB 6TPP · PDBe 6TPP · UniProt A0A0S2UQQ5

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