Research workbench
Structure of FANCD2 homodimer
Analyse Structure of FANCD2 homodimer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6TNI
- Type
- protein
- Length
- 2,134 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- F1NP22
- Pockets
- 20 · best druggability 0.83
Structure
electron microscopy · 1 distinct chain · 60% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, a | Uncharacterized protein | protein | 1067 | 60% helix, 1% strand | F1NP22 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1017 | 0.83 | 0.84 | 150 | empty |
| 2 | 756 | 0.83 | 0.86 | 116 | empty |
| 3 | 970 | 0.82 | 0.84 | 153 | empty |
| 4 | 880 | 0.82 | 0.84 | 103 | empty |
| 5 | 841 | 0.81 | 0.84 | 114 | empty |
Interfaces
1 interface between chains.
- A–a · 1274 Ų buried · 10 hydrogen bonds · protein-protein
Compared structures
- 6TNI · Structure of FANCD2 homodimer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F1NP22
- Elsewhere: RCSB PDB 6TNI · PDBe 6TNI · UniProt F1NP22
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