Research workbench
Linalool dehydratase isomerase C171A mutant
Analyse Linalool dehydratase isomerase C171A mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6TFT
- Type
- protein
- Length
- 1,817 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Linalool dehydratase-isomerase protein ldi
- UniProt
- W8X534
- Pockets
- 15 · best druggability 0.72
Structure
x-ray diffraction · 5 distinct chains · 56% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Linalool dehydratase-isomerase protein ldi | protein | 365 | 56% helix, 7% strand | W8X534 |
| B | Linalool dehydratase-isomerase protein ldi | protein | 364 | 56% helix, 7% strand | W8X534 |
| C | Linalool dehydratase-isomerase protein ldi | protein | 364 | 56% helix, 7% strand | W8X534 |
| D | Linalool dehydratase-isomerase protein ldi | protein | 363 | 56% helix, 7% strand | W8X534 |
| E | Linalool dehydratase-isomerase protein ldi | protein | 361 | 57% helix, 7% strand | W8X534 |
Pockets
15 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 62 | 0.72 | 0.97 | 21 | empty |
| 2 | 55 | 0.71 | 0.98 | 22 | empty |
| 3 | 61 | 0.71 | 0.97 | 22 | empty |
| 4 | 50 | 0.70 | 0.98 | 20 | empty |
| 5 | 52 | 0.68 | 0.96 | 23 | empty |
Interfaces
5 interfaces between chains.
- A–B · 1238 Ų buried · 12 hydrogen bonds · protein-protein
- C–E · 1237 Ų buried · 13 hydrogen bonds · protein-protein
- A–D · 1226 Ų buried · 12 hydrogen bonds · protein-protein
- B–C · 1220 Ų buried · 11 hydrogen bonds · protein-protein
- D–E · 1199 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 6TFT · Linalool Dehydratase Isomerase C171A mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt W8X534
- Elsewhere: RCSB PDB 6TFT · PDBe 6TFT · UniProt W8X534
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