Research workbench
The structure of BCL-W reveals a role for the C-terminal residues in modulating biological activity
Analyse The structure of BCL-W reveals a role for the C-terminal residues in modulating… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1O0L
- Type
- protein
- Length
- 188 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Apoptosis regulator BCL-W
- UniProt
- Q92843
- Pockets
- 2 · best druggability 0.48
Structure
solution nmr · 1 distinct chain · 62% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Apoptosis regulator BCL-W | protein | 188 | 62% helix, 0% strand | Q92843 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 59 | 0.48 | 0.85 | 19 | empty |
| 2 | 64 | 0.42 | 0.81 | 18 | empty |
Compared structures
- 1O0L · The structure of BCL-W reveals a role for the C-terminal residues in modulating… · the same entry in another collection · chain A against A, TM-score 1.00
- Q92843 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 2 (Q92843) · a predicted model of the same protein · chain A against A, TM-score 0.82
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92843
- Elsewhere: RCSB PDB 1O0L · PDBe 1O0L · UniProt Q92843
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