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Crystal structure of the epimerization domain from the third module of tyrocidine synthetase B, TYCB3(E)

Analyse Crystal structure of the epimerization domain from the third module of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6TA8
Type: protein
Length: 887 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Tyrocidine synthase 2
EC: 5.1.1.11
UniProt: O30408
Pockets: 9 · best druggability 0.83

Structure

x-ray diffraction · 2 distinct chains · 38% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tyrocidine synthase 2 (EC 5.1.1.11)	protein	438	38% helix, 22% strand	O30408
B	Tyrocidine synthase 2 (EC 5.1.1.11)	protein	449	38% helix, 22% strand	O30408

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	899	0.83	0.85	83	empty
2	640	0.79	0.84	61	empty
3	53	0.71	0.98	16	empty
4	288	0.60	0.79	27	empty
5	124	0.50	0.80	15	empty

Interfaces

1 interface between chains.

A–B · 334 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

6TA8 · Crystal structure of the epimerization domain from the third module of tyrocidine… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O30408
Elsewhere: RCSB PDB 6TA8 · PDBe 6TA8 · UniProt O30408

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