Research workbench
The rec domain of xync, a response regulator from geobacillus stearothermophilus
Analyse The rec domain of xync, a response regulator from geobacillus stearothermophilus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6SWL
- Type
- protein
- Length
- 263 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Two-component response regulator
- UniProt
- Q09LZ6
- Ligands
- MG
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Two-component response regulator | protein | 133 | 46% helix, 19% strand | Q09LZ6 |
| B | Two-component response regulator | protein | 130 | 42% helix, 18% strand | Q09LZ6 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 583 | 0.67 | 0.77 | 52 | empty |
Interfaces
1 interface between chains.
- A–B · 589 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (phosphorylation).
Compared structures
- 6SWL · The REC domain of XynC, a response regulator from Geobacillus stearothermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q09LZ6
- Elsewhere: RCSB PDB 6SWL · PDBe 6SWL · UniProt Q09LZ6
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