Research workbench

Crystal structure of TCDB2-TCCC3-tev

Analyse Crystal structure of TCDB2-TCCC3-tev in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6SUQ
Type: protein
Length: 2,134 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TCDB2,TCCC3,GENOME polyprotein
EC: 3.4.-.-, 3.4.22.45, 3.6.4.-, 3.4.22.44, 2.7.7.48
UniProt: Q8GF99, Q8GF97, P04517
Pockets: 20 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 8% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TCDB2,TCCC3,GENOME polyprotein (EC 3.4.-.-, 3.4.22.45, 3.6.4.-, 3.4.22.44, 2.7.7.48)	protein	2134	8% helix, 40% strand	Q8GF99, Q8GF97, P04517

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1013	0.82	0.83	125	empty
2	122	0.77	0.96	26	empty
3	289	0.75	0.88	30	empty
4	554	0.75	0.82	71	empty
5	648	0.70	0.78	71	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6SUQ · Crystal Structure of TcdB2-TccC3-TEV · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8GF99
Every structure of UniProt Q8GF97
Every structure of UniProt P04517
Elsewhere: RCSB PDB 6SUQ · PDBe 6SUQ · UniProt Q8GF99 · UniProt Q8GF97 · UniProt P04517

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.