Research workbench
Structure of ECCB3 dimer from the esx-3 core complex
Analyse Structure of ECCB3 dimer from the esx-3 core complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6SGY
- Type
- protein
- Length
- 804 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Esx-3 secretion system protein ECCB3
- UniProt
- A0QQ39
- Pockets
- 17 · best druggability 0.84
Structure
electron microscopy · 1 distinct chain · 12% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Esx-3 secretion system protein ECCB3 | protein | 402 | 12% helix, 25% strand | A0QQ39 |
Pockets
17 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1136 | 0.84 | 0.85 | 105 | empty |
| 2 | 175 | 0.65 | 0.85 | 32 | empty |
| 3 | 209 | 0.63 | 0.83 | 38 | empty |
| 4 | 71 | 0.59 | 0.89 | 24 | empty |
| 5 | 50 | 0.57 | 0.91 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 932 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0QQ39
- Elsewhere: RCSB PDB 6SGY · PDBe 6SGY · UniProt A0QQ39
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