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Apo form of the ribonucleotide reductase nrdb protein from leeuwenhoekiella blandensis

Analyse Apo form of the ribonucleotide reductase nrdb protein from leeuwenhoekiella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6SF4
Type: protein
Length: 591 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ribonucleoside-diphosphate reductase, beta subunit 1
EC: 1.17.4.1
UniProt: A3XHF9
Pockets: 5 · best druggability 0.60

Structure

x-ray diffraction · 2 distinct chains · 78% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ribonucleoside-diphosphate reductase, beta subunit 1 (EC 1.17.4.1)	protein	296	78% helix, 1% strand	A3XHF9
B	Ribonucleoside-diphosphate reductase, beta subunit 1 (EC 1.17.4.1)	protein	295	78% helix, 1% strand	A3XHF9

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	173	0.60	0.82	24	empty
2	158	0.60	0.83	23	empty
3	156	0.49	0.78	26	empty
4	61	0.37	0.79	16	empty
5	81	0.36	0.76	13	empty

Interfaces

1 interface between chains.

A–B · 1701 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

6SF4 · Apo form of the ribonucleotide reductase NrdB protein from Leeuwenhoekiella blandensis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A3XHF9
Elsewhere: RCSB PDB 6SF4 · PDBe 6SF4 · UniProt A3XHF9

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