Research workbench

Crystal structure of human STARD10

Analyse Crystal structure of human STARD10 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6SER
Type: protein
Length: 245 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Start domain-containing protein 10
UniProt: Q9Y365
Ligands: PO4
Pockets: 3 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Start domain-containing protein 10	protein	245	27% helix, 36% strand	Q9Y365

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A
PEG · Di(hydroxyethyl)ether · additive · 4 copies · chains A
PGE · Triethylene glycol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	766	0.83	0.86	56	PEG, PGE
2	156	0.58	0.82	21	PEG
3	62	0.39	0.80	19	empty

Compared structures

6SER · Crystal structure of human STARD10 · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y365 · AlphaFold monomer V2.0 prediction for start domain-containing protein 10 (Q9Y365) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y365
Elsewhere: RCSB PDB 6SER · PDBe 6SER · UniProt Q9Y365

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.