Research workbench

Structure of type II terpene cyclase MSTE_D109N from scytonema in complex with geranylgeranyl dihydroxybenzoate (substrate)

Analyse Structure of type II terpene cyclase MSTE_D109N from scytonema in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6SBE
Type: protein
Length: 352 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mste
UniProt: A0A2D1CM82
Ligands: L4E
Pockets: 4 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 7% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mste	protein	352	53% helix, 7% strand	A0A2D1CM82

Ligands and binding sites

L4E · geranylgeranyl dihydroxybenzoate · ligand · chains A
GOL · Glycerol · additive · 6 copies · chains A
PEG · Di(hydroxyethyl)ether · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	261	0.79	0.91	33	L4E
2	152	0.44	0.75	31	GOL
3	112	0.39	0.75	20	empty
4	89	0.35	0.75	18	empty

Compared structures

6SBE · Structure of type II terpene cyclase MstE_D109N from Scytonema in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2D1CM82
Elsewhere: RCSB PDB 6SBE · PDBe 6SBE · UniProt A0A2D1CM82

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.