Research workbench
Structure of the icam-1-binding PFEMP1 IT4VAR13 dblbeta domain
Analyse Structure of the icam-1-binding PFEMP1 IT4VAR13 dblbeta domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6S8T
- Type
- protein
- Length
- 442 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Erythrocyte membrane protein 1
- UniProt
- E0A3B3
- Pockets
- 7 · best druggability 0.62
Structure
x-ray diffraction · 1 distinct chain · 53% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Erythrocyte membrane protein 1 | protein | 442 | 53% helix, 2% strand | E0A3B3 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.62 | 0.89 | 19 | empty |
| 2 | 306 | 0.61 | 0.79 | 42 | empty |
| 3 | 142 | 0.60 | 0.85 | 19 | empty |
| 4 | 77 | 0.54 | 0.86 | 17 | empty |
| 5 | 97 | 0.36 | 0.74 | 20 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 6S8T · Structure of the ICAM-1-binding PfEMP1 IT4var13 DBLbeta domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E0A3B3
- Elsewhere: RCSB PDB 6S8T · PDBe 6S8T · UniProt E0A3B3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.