Research workbench
Structure of the beta class N6-adenine DNA methyltransferase rsri bound to S-adenosyl-L-homocysteine
Analyse Structure of the beta class N6-adenine DNA methyltransferase rsri bound to… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1NW7
- Type
- protein
- Length
- 271 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Modification methylase rsri
- EC
- 2.1.1.72
- UniProt
- P14751
- Ligands
- SAH, CL
- Pockets
- 3 · best druggability 0.58
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Modification methylase rsri (EC 2.1.1.72) | protein | 271 | 34% helix, 23% strand | P14751 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 69 | 0.58 | 0.88 | 15 | empty |
| 2 | 202 | 0.46 | 0.74 | 35 | CL, SAH |
| 3 | 67 | 0.30 | 0.74 | 14 | SAH |
Compared structures
- 1NW7 · Structure of the beta class N6-adenine DNA methyltransferase RsrI bound to… · the same entry in another collection · chain A against A, TM-score 1.00
- P14751 · AlphaFold monomer V2.0 prediction for modification methylase rsri (P14751) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14751
- Elsewhere: RCSB PDB 1NW7 · PDBe 1NW7 · UniProt P14751
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